acetylcholinesterase相关论文
纳米材料的生物相容性是人们关注的热点.氧化石墨烯是一种被广泛应用于生物医学的纳米材料,但其毒性不容忽视.本文从溶血率、红细......
Neuroprotective effect of the ethanol extract of Artemisia capillaris on transient forebrain ischemi
Artemisia capillaris Thunberg is a medicinal plant used as a traditional medicine in many cultures.It is an effective re......
Sequence alignments and structural comparisons of insecticides targeting acetyl cholinesterase and t
Insecticides are one of main tools to protect crops from the damage of pests in agriculture.and also bring several negat......
The research in mechanism and impact of different exercise tolerance regularly on space learning-mem
Objective To investigate the possible effects of different exercise intensity on learning-memory of space in aged rats a......
Fucoxanthin,a marine carotenoid,reverses scopolamine-induced cognitive impairments in mice and inhib
Fucoxanthin,a natural carotenoid abundant in edible brown seaweeds,has been shown to possess anti-cancer,anti-obesity,an......
Galantamine,a novel cholinergic agent with a dual mode of action,on cognitive deficits in animal mod
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Acanthopanax sessiliflorus Seemann (Araliaceae) is a shrub and growing widely in Korea and China.Its root barks (Acantho......
Uncaria rhynchophylla (Rubiaceae) is a woody plant and widely distributed in China and other East Asia.Its hooks (Ramulu......
Biochemistry test was employed for the detection of acetylcholinesterase(AchE) level in susceptible mosquitoes and resis......
Chromatic Sensor Strips Based on Acetylcholinesterase Immoblized Nanofibrous Membranes for Dimethoat
A facile,ultrasensitive and selective sensor strip utilizing crosslinked electrospun poly (vinyl alcohol) (PVA) nanofibr......
Acetylcholinesterase (AChE) is highly active for the hydrolysis of acetylcholine (ACh) and can regulate the concentratio......
Sepsis Strengthens Antagonistic Actions of Neostigmine on Rocuronium in a Rat Model of Cecal Ligatio
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A series of graveolinine derivatives were synthesized from 1-(2-aminophenyl)ethanone by four steps,all the compounds......
Protein Cage Encoded Lead Phosphate Tags Amplified Ultrasensitive Quantification of Phosphorylated A
A new magnetic nanoparticle sandwich-like immunoassay has been developed for quantification of phosphorylated acetyl......
In Situ Formation of Metal Coordination Polymer a New Strategy for Fluorescence Turn-on Assay of Ace
A novel method for the sensing of acetylcholinesterase (AChE) activity and inhibitor screening based on the formation of......
Forsythiaside A(3,4-dihydroxy-β-phenethyl-O-α-L-rhamnopyranosyl-(1→6)-4-O-caffeoyl-β-D-glucopyranoside),which wa......
Mechanisms of Oganophosphate Rsistance in a Feld Ppulation of Oiental Mgratory Lcust,Locusta migrato
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Sesquiterpenes and a monoterpenoid with acetylcholinesterase (AchE) inhibitory activity from Valeria
Acetylcholinesterase Inhibitor (AchEI) is the most extensive in all anti-dementia drugs.The extracts and isolated co......
Chronic exposure to low-levels of organophosphate (OP) compounds, such as chlorpyrifos (CPF), induces oxidative stre......
[Objectives]The anti-tumor,anti-bacterial,anti-acetylcholinesterase and anti-α-glucosidase activity in vitro of five ch......
应用电镜下乙酰胆碱酯酶定位方法,观察了甲状腺素对大鼠膈肌神经肌肉接头的影响。结果表明,甲状腺素可引起膈肌3种肌纤维神经肌肉......
在有一种杀虫剂的 butyrylcholinesterase 之间的 Phosphonylation 和老化过程在 B3LYP/6-311G 被学习了(d, p ) 理论的水平。计算......
用MNDO半经验法,计算了乙酰胆碱酯酶抑制剂他克林及其类似物的优化构型、前线轨道,电荷分布。并以这些量子化学参数讨论了它们抑制AChE的机制......
Acetylcholinesterase (AChE) inhibitors are an important class of medicinal agents used for the treatment of Alzheimer......
Effect of propofol on the reactivity of acetylcholinesterase, N-methyl-D-aspartate receptors, and ga
We induced ischemic brain injury in aging rats to examine the effects of varying doses of propofol on hippocampal activi......
Acetylcholinesterase (AChE) was immobilized on multilayer films assembled by poly diallyldimethylammoniumrnchloride (PDD......
Ameliorating effect of Zhizi (Fructus Gardeniae) extract and its glycosides on scopolamine-induced m
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In vitro antioxidant assessment and a rapid HPTLC bioautographic method for the detection of anticho
OBJECTIVE: Geophila repens(L.) I. M. Johnst.(Rubiaceae), a small, creeping, perennial herb, is claimed to have memory-en......
Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with
Objective:This study investigated the ameliorative potential of Zingiber officinale Roscoe extract against lead-induced ......
目的 研究氟对慢性氟中毒大鼠学习、记忆功能的影响以及其可能的机制,探讨氟对脑组织胆碱酯酶活性的影响多氟中毒大鼠智力损伤程度......
目的 观察燃煤污染型氟中毒大鼠学习记忆能力的变化,探讨其发生机制.方法 健康SD大鼠48只,按染氟剂量分为对照、低氟、高氟3组.低......
目的 观察血浆丁酰胆碱酯酶(BuChE)活性在急性有机磷农药中毒(AOPP)诊断中的意义,分析乙酰胆碱酯酶(ACHE)和BuChE的相关性,并对BuC......
Anti-acetylcholinesterase activity of the aglycones of phenolic glycosides isolated from Leonurus ja
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Phytochemical composition of Caesalpinia crista extract as potential source for inhibiting cholinest
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Protective effect of ashwagandha (Withania somnifera) against neurotoxicity induced by aluminum chlo
Objective:To evaluate the neuroprotective effect of ashwagandla extract against aluminum chloride-induced neurotoxicity ......
本文通过对荣华二采区10...
OBJECTIVE:To examine the efficacy of Silene arenosa extract on acetylcholinesterase(AChE)of krait(Bungarus Sindanus)snak......
Effect of bilobalide B on cholinergic hippocampal neurons exposed to cholesterol and apoliprotein E4
BACKGROUND: Extracts of ginkgo biloba leaves have been reported to improve nerve function and activity in Alzheimers dis......
Changes of biochemical indices in brain, liver tissue and serum in mice with Alzheimer disease after
BACKGROUND: Alzheimer disease is a main type of dementia, and the important clinical characteristic is the rapid decline......
Brain injury due to acute organophosphate poisoning Magnetic resonance imaging manifestation and pat
BACKGROUND: Acute organophosphate poisoning can cause injuries of multiple visceras; especially,central nervous system i......
昆虫乙酰胆碱酯酶(acetylcholinesterase,AChE,EC 3.1.1.7)是有机磷和氨基甲酸酯类杀虫剂的作用靶标.利用RT-PCR和RACE技术从蓖麻......
目的为了克服上市药物伊立替康酶转化率低、个体差异大以及由乙酰胆碱酯酶抑制作用而引发的毒副作用等不足,设计合成高效低毒的新......
目的 观察石杉碱甲(Hup A)与石杉碱乙(Hup B)不同比例组合物抗乙酰胆碱酯酶(AChE)活性及安全性的影响.方法 采用比色法检测Hup A与......
目的对海洋真菌Aspergillus sp.SCS-KFD03的发酵液中化学成分进行分离鉴定,并测定其生物活性。方法采用硅胶柱色谱、Sephadex LH-2......
乙酰胆碱水平降低或活性异常是阿尔茨海默病发生的主要原因,通过抑制乙酰胆碱酯酶的活性,提高乙酰胆碱水平可以治疗阿尔茨海默病。......